Hi VJFRanzk - wondering if you can post an update on this thread since I'm making the same audio interface buying decisions myself right now (12/31/12 - Happy New Year!) I also prefer Ableton and from my perspective, the absolute MOST important thing I'm looking for is non-glitch functionality. Color and "noise level" are secondary concerns for me. This said, the C400 is getting really good reviews as being a solid, best-band-for-the-buck device, But the Focusrite interfaces ship with a lite version of Ableton, which leads me to think that although the A/D converters may not be a transparent as MOTU, that the Focusrite stuff may work better because of their relationship with Ableton.
One last note as to my hardware, software, and mission: I am using an Asus Vivobook x202e that has two USB2 and one USB3 port for connectivity and I am running Ableton 8 Suite with no problems, as well as a Novation Launchpad and Korg Kontrol 49.
My goal is to be able to record and launch clip loops as well as effects from my midi controller - similar to what Kid Beyond is doing. PS: Are there any templates that can help me out in this direction any one knows of?