Hello Spidergod!
Well, just tried it right now with the Axiom preset in MIDI/Sync tab. My set-up was the following:
- - Control Surface: Axiom
- Input: USB Axiom 25 (Port 1)
- Output: USB Axiom 25 (Port 1)
- Input port configuration for USB Axiom 25 (Port 1): Track ON, Sync OFF, Remote ON
- The second input and output: All OFF
I figured out that the default Preset 20 works quite reasonable. Once you switch the track, device or filter with the blue hand can be controlled by Axiom's knobs. Unfortunately the mapping is unknown for me. The device racks are quite straight-forward: two rows by four knobs. But for instance more complicated gadgets like Auto Filter — no-one knows.
You are right that there is in the MIDI Mapping perspective nothing. But still — I am able to assign any knob to another thing. In that case the original mapping that came from the Control Surface is disabled for the particular knob and the knob is following the new mapping.
As I sad at the total beginning: I'm not using Control Surfaces at all. I prefer instant fun instead of solid solution.

It's mainly because of I started with version 5 (and later 6) with M-Audio Ozone that was unsupported as a Control Surface. Than I upgraded directly to version 8 but I'm simply lazy to learn new tricks in this; especially if instant mapping was/is exactly what I was looking for.
By the way — Axiom is Class Compliant and should not require any drivers. It should apply not only for OS X but for Windows (any version) as well.
A few weeks ago I read one or two posts from one guy with Axiom Pro 49 or 61. It seems products of M-Audio are designed mainly for headaches.
Till you will be looking for a solution you can use my
instant fun approach:
- - I/O configuration is the same as above except Control Surface which is set to None
- Axiom Preset: 17 (factory default)
This is working well for me. Knobs and transport buttons are free for you, pads are working with Impulse.
There is only a small problem with Drum Racks — pads are one octave up — but you can solve it with Enigma.
Anyway — is the MIDI Mapping working for you if Axiom is not in Control Surface mode?
Good luck!
PETR
P.S.: Excuse me for delayed response. I was at work and Axiom is at home. I spent a while with reconfiguration as well.