Here's a quick test:
1) Fire up Battery or any other drum sampler
2) Lay down a simple pattern
3) Flip Live's main audio buffer to 2048 or as high as yours will go
4) Set plug-in buffer size to "as audio buffer"
5) Turn on your click and play the sequence
6) Observe MAJOR sync issue!
EDIT: video here - http://youtu.be/1ZmIYrGnz6A?hd=1
Even when working with a smaller main buffer setting, your plugins will still run with latency... Only remedy is to keep plug-in buffer at 32 samples, which of course takes a major hit on CPU!
Can someone else please confirm this? ..I do like wonky beats, but DAMN, ABLETON!!
Setup: iMac i5, 10.6.8, Saffire Pro 40 (MixControl 3.0), TI chipset, Live 8.3.3, Battery 3.2.3